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Brachydactyly type A2

1 OMIM reference -
3 associated genes
6 signs/symptoms

PROTEIN INTERACTIONS: 4

Hereditary mixed polyposis syndrome

2 OMIM references -
2 associated genes
No signs/symptoms info

Brachydactyly type A2

Hereditary mixed polyposis syndrome

BMP2	(UniProt - OMIM)		BMPR1A	(UniProt - OMIM)
BMPR1B	(UniProt - OMIM)		GREM1	(UniProt - OMIM)
GDF5	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	BMP2 GDF5 BMPR1B BMP2	(0.9) (0.89) (0.75) (0.52)	BMPR1A BMPR1A BMPR1A GREM1

Citations in the biomedical literature:

Brachydactyly type A2		Hereditary mixed polyposis syndrome
	Synonym(s): - Brachydactyly, Mohr-Wriedt type		Synonym(s): (no synonyms)

	Classification (Orphanet): - Rare bone disease - Rare developmental defect during embryogenesis - Rare genetic disease		Classification (Orphanet): - Rare gastroenterologic disease - Rare genetic disease - Rare oncologic disease

	Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -		Classification (ICD10): - Neoplasms -

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: neonatal/infancy Average age of death: - Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: - Average age onset: childhood Average age of death: - Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - 1 MeSH reference: C537089		External references: 2 OMIM references - No MeSH references

Brachydactyly type A2
	Very frequent - Autosomal dominant inheritance - Short hand / brachydactyly Frequent - Clinodactyly of fifth finger - Short foot / brachydactyly of toes Occasional - Metacarpal anomalies / Archibald's sign - Terminal / third phalangeal bone of fingers hypoplasia
Hereditary mixed polyposis syndrome
(no data available)